FBS Conferences Based on Geography:
Northwest Conference
Boise St.
Oregon
Oregon St.
Washington
Washington St.
Pacific Ocean Conference
Cal
Fresno St.
Hawaii
Nevada
San Jose St.
SDSU
Stanford
UCLA
UNLV
USC
Rocky Mountain Conference
Air Force
Arizona
Arizona St.
BYU
Colorado
Colorado St.
New Mexico
New Mexico St.
Utah
Utah St.
UTEP
Wyoming
Lone Star Conference
Baylor
Houston
North Texas
Rice
SMU
TCU
Texas
Texas A&M
Texas St.
Texas Tech
UTSA
Mississippi River Conference
Arkansas St.
Lousiana Tech
LSU
Memphis
Mississippi St
Ole Miss
Southern Miss
Tulane
ULL
ULM
Heartland Conference
Arkansas
Kansas
Kansas St.
Missouri
Nebraska
Oklahoma
Oklahoma St.
Tulsa
Gatorland Conference
Alabama
Auburn
FAU
FIU
Florida
Florida St.
Georgia Southern
Miami Fl.
South Alabama
Troy
UAB
UCF
USF
Dixieland Conference
Clemson
Georgia
Georgia St.
Georgia Tech
MTST
South Carolina
Tennessee
Vanderbilt
Atlantic Ocean Conference
Appalachin St.
Charlotte
Coastal Carolina
Duke
East Carolina
Liberty
NCST
Old Dominion
UNC
Virginia
Virginia Tech
Wake Forest
Lakeland Conference
Illinois
Iowa
Iowa St.
Minnesota
Northern Illinois
Northwestern
Purdue
Wisconsin
Tri-Border Conference
Akron
Bowling Green St.
Central Michigan
Eastern Michigan
Kent St.
Michigan
Michigan St.
Notre Dame
Toledo
Western Michigan
Ohio River Conference
Ball St.
Cincinnati
Indiana
Kentucky
Louisville
Marshall
Miami OH
Ohio
Ohio St.
Western Kentucky
Pilgrim Conference
Marshall
Maryland
Navy
Penn St.
Pittsburgh
Temple
Evergreen Conference
Army
Boston College
Buffalo
Rutgers
Syracuse
UCONN
UMASS
I've thought of this idea for many years. To imagine how leagues would be for all sports, especially football and basketball.
Luckily, if you have a college football video game you can reorganize the conferences so you can play with this set up to see for yourself how it would go.